Variables

Culture positive(n = 30)

Culture negative (n = 45)

p value

Age yrs (mean ± SD)

22.49 ± 13.02

30.78 ± 18.7

0.027

Sex (male/female), n

20/10

32/13

0.683

Underlying heart disease

RHD

11 (36.7%)

20 (44.4%)

0.660

CHD

15 (50.0%)

11 (24.4%)

0.04

Prosthetic valve

3 (10.0%)

4 (8.9%)

0.80

No structural heart disease

6 (20.0%)

2 (4.4%)

0.07

Degenerative heart disease

0 (0.0%)

2 (4.4%)

0.66

Prior antibiotic therapy

9 (30.0%)

31 (68.9%)

0.002

Vegetation Size

<10 mm (small)

15 (50.0%)

22 (48.9%)

0.88

>10 mm (large)

15 (50.0%)

23 (51.1%)

0.88

Complications

Congestive heart failure (CCF)

15 (50.0%)

17 (37.8%)

0.209

Neurological abnormalities

11 (36.7%)

8 (17.7%)

0.11

Renal failure

8 (26.7%)

12 (26.7%)

0.79

Embolism (digital infarcts, CV stroke, splenic infarcts)

8 (26.7%)

10 (22.2%)

0.86

Abscess

Renal abscess

0 (0.0%)

3 (6.7%)

0.39

Aortic root abscess

2 (6.7%)

1 (2.2%)

0.72

Splenic abscess

0 (0.0%)

2 (4.4%)

0.66

Surgery

2 (6.7%)

10 (22.2%)

0.14

Death

12 (40.0%)

10 (22.2%)

0.16

Variables

Culture positive (n = 30)

Culture negative (n = 45)

p value

Age yrs (mean ± SD)

22.49 ± 13.02

30.78 ± 18.7

0.027

Sex (male/female), n

20/10

32/13

0.683

Underlying heart disease

RHD

11 (36.7%)

20 (44.4%)

0.660

CHD

15 (50.0%)

11 (24.4%)

0.04

Prosthetic valve

3 (10.0%)

4 (8.9%)

0.80

No structural heart disease

6 (20.0%)

2 (4.4%)

0.07

Degenerative heart disease

0 (0.0%)

2 (4.4%)

0.66

Prior antibiotic therapy

9 (30.0%)

31 (68.9%)

0.002

Vegetation Size

<10 mm (small)

15 (50.0%)

22 (48.9%)

0.88

>10 mm (large)

15 (50.0%)

23 (51.1%)

0.88

Complications

Congestive heart failure (CCF)

15 (50.0%)

17 (37.8%)

0.209

Neurological abnormalities

11 (36.7%)

8 (17.7%)

0.11

Renal failure

8 (26.7%)

12 (26.7%)

0.79

Embolism (digital infarcts, CV stroke, splenic infarcts)

8 (26.7%)

10 (22.2%)

0.86

Abscess

Renal abscess

0 (0.0%)

3 (6.7%)

0.39

Aortic root abscess

2 (6.7%)

1 (2.2%)

0.72

Splenic abscess

0 (0.0%)

2 (4.4%)

0.66

Surgery

2 (6.7%)

10 (22.2%)

0.14

Death

12 (40.0%)

10 (22.2%)

0.16